If you have lost 5 of your weight within three months, there is no restriction on how long orlistat may be prescribed.
Information about Orlistat.
Pregnancysee Use in Specific PopulationsPatients with chronic malabsorption syndrome Patients with cholestasis Patients with known hypersensitivity to XENICAL or to any component of this product.
The dose-response relationship for orlistat in human volunteers is shown in Figure 1The effect is the percentage of ingested fat excretedreferred to as fecal fat excretion percentageBoth individual dataopen circlesand the curve predicted for the population with the maximum-effect modelcontinuous lineare shown in Figure 1.
Orlistat had no detectable mutagenic or genotoxic activity as determined by the Ames testa mammalian forward mutation assayV79/HPRTan in vitro clastogenesis assay in peripheral human lymphocytesan unscheduled DNA synthesis assayUDSin rat hepatocytes in cultureand an in vivo mouse micronucleus test.
Data from a XENICAL and cyclosporine drug interaction study indicate a reduction in cyclosporine plasma levels when XENICAL was coadministered with cyclosporineThereforeXENICAL and cyclosporine should not be simultaneously coadministeredTo reduce the chance of a drug-drug interactioncyclosporine should be taken at least 3 hours before or after XENICAL in patients taking both drugsIn additionin those patients whose cyclosporine levels are being measuredmore frequent monitoring should be considered.
It blocks your body from absorbing about a third of the fat you eatWhen a doctor prescribes orlistatit’s called XenicalIf you get it without a prescriptionit’s called Alliwhich has half of Xenical’s doseIt’s approved for long-term use.
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