Estrace vaginal cream estradiol topical is a member of the estrogens drug class and is commonly used for atrophic urethritis and atrophic vaginitis.

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Estrace tablets 2 mgcontain FD&C Yellow No5tartrazinewhich may cause allergic-type reactionsincluding bronchial asthmain certain susceptible individualsAlthough the overall incidence of FD&C Yellow No5tartrazinesensitivity in the general population is lowit is frequently seen in patients who also have aspirin hypersensitivity.
Systemic absorption may occur with the use of ESTRACE CREAMThe warningsprecautionsand adverse reactions associated with oral estrogen treatment should be taken into account.
Long-term continuous administration of estrogenwith and without progestinin women with and without a uterushas shown an increased risk of endometrial cancerbreast cancerand ovarian cancerSee BOXED WARNINGSWARNINGS and PRECAUTIONS
Breast lumpspossible breast cancerask your doctor or health professional to show you how to examine your breasts monthly)
Large doses of estrogen5 mg conjugated estrogens per daycomparable to those used to treat cancer of the prostate and breasthave been shown in a large prospective clinical trial in men to increase the risks of nonfatal myocardial infarctionpulmonary embolismand thrombophlebitis.
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estrace may also be used in the treatment of cancer in both men and women.