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Risk of ovarian enlargementovarian hyperstimulation syndromeOHSStransient liver function test abnormalities suggestive of hepatic dysfunctionwhich may be accompanied by morphologic changes on liver biopsyreported in association with OHSSwhich is a medical event distinct from uncomplicated ovarian enlargementdeath due to hypovolemic shockhemoconcentrationor thromboembolism has occurredif enlargement of ovary occursadditional therapy should not be given until ovaries have returned to pretreatment sizeand dosage or duration of next course should be reducedovarian enlargement and cyst formation associated with therapy usually regresses spontaneously within a few days or weeks after discontinuing treatmentpotential benefit of subsequent therapy in these cases should exceed risk.
ClomiPHENE citrate is a drug of considerable pharmacologic potencyWith careful selection and proper management of the patientclomiPHENE citrate has been demonstrated to be a useful therapy for the anovulatory patient desiring pregnancy.
Clomiphene may also be used for purposes other than those listed in this medication guide.
Prolonged use of clomiphene citrate tablets USP may increase risk of a borderline or invasive ovarian tumor.
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