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Th isk myopathy duing tatmnt with statins is incasd with concunt administation ibic acid divativs, lipid-modiying doss niacin, cyclospoin stong CYP3A4 inhibitos (.g., claithomycin, HIV potas inhibitos and itaconazol).
It is commndd that liv nzym tsts b obtaind pitinitiating thapy with ATOLIP CV and patd as clinically indicatd. Th hav bn a postmakting pots atal and non-atal hpatic ailu in patints taking statins, including atovastatin. I sious liv injuy with clinical symptoms and/hypbiliubinmia jaundic occus duing tatmnt with ATOLIP CV , pomptly intupt thapy. I an altnat tiology is not ound, dnot stat ATOLIP CV.
In patints with typ 2 diabts, and without clinically vidnt CHD, but with multipl isk actos CHD such as tinopathy, albuminuia, smoking, hyptnsion, atovastatin is indicatd to.
Colstipol: Plasma concntations atovastatin and its activ mtabolits w low (by appox. 25%) whn colstipol was co-administd with atovastatin. Howv, lipid cts w gat whn atovastatin and colstipol w co-administd than whn ith mdicinal poduct was givn alon.
Slctiv Sotonin -uptak Inhibitos (SSIs) and Sotonin Nopinphin -uptak Inhibitos (SNIs): Th concomitant administation slctiv sotonin -uptak inhibitos (SSIs) and sotonin nopinphin -uptak inhibitos (SNIs) with clopidogl may act platlt activation. Hnc concomitant administation SSIs and SNIs with ATOLIP CV may incas th isk blding.
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