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Information about Pletal.
Caution should be exercised when prescribing cilostazol for patients with atrial or ventricular ectopy and patients with atrial fibrillation or flutter.
Pletal and several of its metabolites inhibit phosphodiesterase III activity and suppress cAMP degradation with a resultant increase in cAMP in platelets and blood vesselsleading to inhibition of platelet aggregation and vasodilationrespectively.
Patients may respond as early as 2 to 4 weeks after the initiation of therapybut treatment for up to 12 weeks may be needed before a beneficial effect is experiencedIf symptoms are unimproved after 3 monthsdiscontinue PLETAL.
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possibly overall effect of pletal cilostazol is supposed to increase blood flow and thus could inprove erections.

