Talk with your doctor about the possibility of vitamin b- 12 deficiency if you have been on nexium for a long time more than 3 years .

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Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.
Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated.
Serum chromogranin ACgAlevels increase secondary to drug-induced decreases in gastric acidityThe increased CgA level may cause false positive results in diagnostic investigations for neuroendocrine tumorsHealthcare providers should temporarily stop esomeprazole treatment at least 14 days before assessing CgA levels and consider repeating the test if initial CgA levels are highIf serial tests are performede.gfor monitoringthe same commercial laboratory should be usedfor testingas reference ranges between tests may varysee CLINICAL PHARMACOLOGY
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