High dose methotrexate treatment may result in neurological problems like difficulty in headache, difficulty in speaking, behavioural abnormalities and seizures.
Information about Methotrexate.
This medicine may affect fertilityability to have childrenin both men and womenHoweverit is important to use birth control to prevent pregnancy because methotrexate may harm the baby if a pregnancy does occur.
Methotrexate is a strong medicationThe dosage and how often you take this medication are based on your medical condition and response to treatmentThere are many different dosing schedules for this medicationespecially for cancer treatmentTaking this medication the wrong way may cause serious side effectsincluding deathThereforeit is very important that you follow your doctor’s instructions carefullyTake this medication by mouth as directed by your doctor.
It is important to discuss any history of allergies to any medicationsor an allergy to any of the ingredients in methotrexate tabletsAsk your doctor or pharmacist for a list of the ingredientsSome antibioticsvitamin supplements and other medications can interact with methotrexate and may require a dose adjustment to avoid serious side effectsThereforeit is vital to discuss with your doctor and pharmacist your list of prescription and non-prescription medications including vitaminsnutritional supplements and herbal products which you are currently taking or plan to takeIf you have one or more of the following conditionsmethotrexate may NOT be a suitable treatment option for you or you may require a lower dose and close monitoringFolatea type of B vitamindeficiency Blood cell or bone marrow disorder Liver disorderespeciallyif caused by excessive alcohol intakeKidney disease Pneumonia or lung disease Stomach ulcers Any infection If you are receiving radiation treatment.
Increased side effects from other drugsTaking methotrexate with certain medications raises your risk of side effects from those drugsExamples of these drugs include:
Drink plenty of fluids while taking this medication unless your doctor tells you otherwiseDoing so helps your kidneys to remove the drug from your body and avoid some of the side effects.
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most people don t have severe or dangerous methotrexate side effects.