Bristol was unsuccessful in its attempt to get congress to extend the patent life of glucophage, and it has also lost out in its legal attempt to have the life of the patent extended through this route also.
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CommentsTake in divided doses 2 to 3 times a day with mealsTitrate slowly to minimize gastrointestinal side effects.
Lactic acidosis is a rarebut potentially severeconsequence of therapy with metforminit is characterized by elevated blood lactate levels5 mmol/Ldecreased blood pHelectrolyte disturbances with an increased anion gapand an increased lactate/pyruvate ratiowhen metformin is implicated as the cause of lactic acidosismetformin plasma concentrations5 mcg/mL are generally found.
Stop taking this medication and tell your doctor right away if this very serious side effect occurslactic acidosissee Warning section
Older adults may be at greater risk for side effects such as low blood sugar or lactic acidosis.
Reasonable care has been taken to provide accurate information at the time of creationThis information is not intended to substitute medical advicediagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical conditionPlease refer to our terms and conditions.
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